Not sure but I think I might be OP and I am now using it daily with Guix and EXWM and it's pretty great. I don't think Nyxt browser (new name) is made useless by EXWM simulation keys since you can do things like execute arbitrary js in the browser via parenscript. I'm not aware of a way to do that with just EXWM. Is it a good idea? Probably not I guess.
I can't offer any encouraging words as far as security -- I definitely don't use it for anything risky like banking etc.
I agree that we still have not recreated the good old days of vimperator/pentadactyl but Nyxt makes me more optimistic.
Web does suck though.