I don't really care all that much. If i had the choice i'd probably go for FastCGI as that's what i have to most experience with and where i can be sure it'll at least cover my basic needs. The only drawback i've discovered over the years (at least in relation to nginx) is the inability to access partial request bodies or chunked uploads in real time. I figure at least CGI wouldn't have this problem but then CGI is vastly inferior when it comes to huge loads i guess so i doubt there is an ideal solution for every use case.